TB-500

TB-500 on this listing is a research peptide sold as a 10 mg lyophilized vial, and its batch certificate identifies the material as thymosin beta-4 (Tβ4), the 43-residue, N-terminally acetylated actin-binding peptide first sequenced from calf thymus.^{6940133, 1999398} The name TB-500 is used in the market both for full-length Tβ4 and for a seven-residue synthetic fragment of it, so this page sets out exactly what the posted certificate for this lot reports. The certificate card for lot RRL-8408241-P sits at the top of the page. For qualified laboratory research only.

Research reagent identity

Doping-control chemists who analysed products sold as TB-500 found the acetylated 17–23 fragment, which is why the name alone does not settle identity.^{22962027, 23084823} For this lot, the certificate’s CAS number, formula, weight and CID all point to the full-length peptide.

Research literature

The material on this listing is identified on its certificate as full-length thymosin beta-4, a 43-residue actin-sequestering peptide. Its actin-binding biochemistry is described in the primary literature. Primary sources are linked below for researchers who need the original papers. This listing does not summarise study outcomes and makes no claim about any effect, use or benefit of this product, which is supplied as a reference material for in vitro laboratory research only.

References (PubMed): PMID 1999398, PMID 1447300, PMID 16099219, PMID 14500546, PMID 15565145, PMID 17108969, PMID 11950239, PMID 15980226, PMID 17495250, PMID 25826322, PMID 34346165

Batch documentation

The certificate card on this page is titled TB-500 and shows batch RRL-8408241-P, purity 99.34%, date 09 JUL 2026, lab horizonanalytical.com. The two PDFs behind the card add the detail:

• Purity report 1016894: UPLC-MS analysis, result 99.34% against a specification of >98%; quantity found 10.15 mg against a 10 mg specification; sample received 07/05/2026, analysed 07/09/2026.
• Endotoxin report 1016893 (lot RRL-8408241-E): result <0.05 EU/mL, marked Pass.
• Identity fields printed on both: CAS 77591-33-4, C₂₁₂H₃₅₀N₅₆O₇₈S, ~4963 g/mol, PubChem CID 16132341. The mass spectrum shows its main ion at m/z 1654.08, which is close to what a peptide of about 4,963 Da gives when it carries three charges (4,963 ÷ 3 ≈ 1,654).

To check a vial, compare the lot number on its label with RRL-8408241-P on the card, then look the report number up with the lab, which states that its certificates are searchable at horizonanalytical.com. Certificates for other products are collected in the Revitalized Research COA library, and the guide on how to verify a peptide COA walks through lab look-ups and warning signs. Batch certificates are posted when available, so a vial from a different lot should be matched to its own paperwork.

Storage and handling

A 43-residue peptide is best kept dry until the day it is needed. Store sealed vials cold, protected from light and moisture, and let a vial reach room temperature before opening so condensation does not form on the cake. Record the lot number and the date of reconstitution on anything prepared from it. Reconstitution water is a separate item (reconstitution solution), and the choice of diluent and volume belongs to the lab’s own protocol. Labs that want a prepared format can compare the TB-500 10 mg pen, and researchers working with both compounds can read BPC-157 vs TB-500 in research or see the TB-500 + BPC-157 blend. General guidance is in peptide storage basics for research labs.

Frequently Asked Questions

TB-500 is listed as a research-use material for qualified laboratory customers. Product information on this page is provided for identification, size or variant selection, ordering, and batch documentation review only. For research use only. Not for human or animal consumption, administration, injection, topical use, medical, clinical, veterinary, food, cosmetic, supplement, household, or other personal use. This site does not provide medical advice, and this product is not intended to diagnose, treat, cure, mitigate, or prevent any disease. These statements have not been evaluated by the Food and Drug Administration. Review the available COA or batch documentation and follow applicable laws, institutional protocols, and safety procedures before handling.

Batch documentation for TB-500 is organized by product, selected variant, and available lot when supplied. Review available COA records, purity or quality documentation, and product identifiers before purchase and before any laboratory handling.

If documentation is not displayed for a selected size or lot, contact support before ordering. Documentation is provided for research recordkeeping and product verification only.

Keep this material sealed until controlled laboratory handling. Store and handle only according to the product label, available COA or SDS, institutional SOPs, and applicable laws.

Use appropriate personal protective equipment and restrict access to qualified personnel. This material is not for human or animal consumption, administration, injection, topical use, medical, clinical, veterinary, food, cosmetic, supplement, household, or other personal use. Dispose of waste according to laboratory protocol and local requirements.